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[DOI] [PubMed] [Google Scholar] 20.Mailloux R.J., McBride S.L., Harper M.-E

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For instance, combining GSH-targeted delivery with chemotherapy, radiotherapy, or immunotherapy can produce synergistic anticancer effects

The consequence of both modifications is to lower glutathione synthesis and cellular levels, thus making this essential co-factor less available to exert its multiple biological functions

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