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First, preclinical studies establish basic safety and efficacy in laboratory and animal models

Weber E, Morgan EE, Iudicello JE, Blackstone K, Grant I, Ellis RJ, et al

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NFATc1-mediated expression of SLC7A11 drives sensitivity to TXNRD1 inhibitors in osteoclast precursors

S., and Singh S

While Cbl plays a crucial role in modulating redox homeostasis, its deficiency has been linked to oxidative stress and various neurological manifestations