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In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, eds

Curcumin is of significant interest for treating leukaemia due to its ability to block stromal protection, thus preventing resistance to chemotherapy (Kelkel et al., 2010)

Thus, the antitumor effect of oltipraz requires Nrf2 function

A Preliminary Report

doi: 10.1038/s41409-020-01152-2 138 TsilifisCLumSHNademiZHambletonSFloodTJWilliamsEJet al

However, earlier data showed an equally dramatic decrease in antigen-specific Ab level elicited by immunization of mice whose B cells were acutely depleted of Rictor to inactivate mTORC2 [133]
