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S1PR2 inhibitors potently reverse 5-FU resistance by downregulating DPD expression in colorectal cancer

doi: 10.1902/jop.2011.100618

Thus, in a comparison of 165 cases and 170 controls for early onset cancer, there was no significant effect of the Pro/Pro genotype on lung cancer risk in smokers or those who never smoked

Gastroenterology 128(1):96107 McGlynn KA, Petrick JL, El-Serag HB (2021) Epidemiology of hepatocellular carcinoma

PMS2 -deficient CRCs tend to exhibit more aggressive behavior and a worse prognosis compared to other MMR-deficient CRCs ( PMS2 -deficient CRCs share more biological characteristics with sporadic MMR-proficient CRCs than with other LS-associated CRCs