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[ 443 ] In a Parkinson's disease mouse model, a substituted benzimidazole (HPPE) aids in releasing BACH1 from DNA binding elements and translocation out of the nucleus, and as an effective and safer analog of heme, it is an underlying therapy for Parkinson's disease

Accordingly, Ortega-Molina et al

doi: 10.3233/JAD-201074

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doi: 10.1091/mbc.e07-05-0491

Current Clinical Trials: Lessons From Failures To date, numerous clinical trials have investigated the efficacy of antioxidants in oxidative stressrelated diseases, although many of them have reported failure results