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First, several studies evaluated the possible effects of ROS on the complex regulation of HIF and identified conflicting roles

American Journal of Human Genetics

Cell 183 (4), 10431057.e15

Fatty acids are categorized based on the number of aliphatic carbon tails: those with fewer than 6, 612, 1321, and more than 21 are considered short-chain fatty acids, medium-chain fatty acids, long-chain fatty acids, and very long-chain fatty acids, respectively [13,14,15]

Additional information Peer review information Nature Communications thanks Yusuke Inoue and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Both these copper ion carriers have shown value in cancer treatment, but their ability to treat cardiovascular disease requires further study (11)
