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doi: 10.3390/ijms242115747 43

127 MendlerM.Eich-BenderS

HIF-1a enhances hypoxia-related glycolysis in cancer cells by activating the expression of multiple glycolytic enzymes, which is crucial for the growth and proliferation of cancer cells under hypoxic conditions 23,24,25

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J., & HLH Across Speciality Collaboration

Since LGSH and MGO, the chemicals responsible for the production of K d-la and K ce , respectively, are mainly produced in the cytosol, it makes sense that these two PTMs occur more frequently on cytosolic proteins that are exposed to these active compounds