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Within this class, flavonoids such as luteolin effectively scavenge free radicals and suppress neuroinflammation [227,228,229], while carotenoids offer similar antidepressant benefits through antioxidant and anti-inflammatory mechanisms [230,231,232,233]
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Maggioni, F., Ruffatti, S., Dainese, F., Mainardi, F

These treatments had low rates of efficacy (5%-20%), high morbidity and mortality and are rarely used today

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