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For ALOX12-knockdown cells, there was a slight increase in CPE during YFV-Asibi and ZIKV infection, while no differences were observed for DENV and YFV-17D (Fig

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Oxidative stress is one of the pathogenic factors for glaucoma and the plasma level of GSH is decreased in primary open angle glaucoma including NTG patients 16,17 , supporting suitability of these mouse models for the basic research of NTG 3,15

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