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Starting low and escalating gradually produced fewer gastrointestinal side effects than starting directly at a higher dose, which is why the 2mg +2mg-every-4-weeks schedule became the standard escalation approach in the published data

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An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution

Needles come in a variety of lengths, typically ranging from 4mm to 12mm, and gauges (thickness), with 31 gauge being the finest