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The Journal of Physiology: Boosting fat burning with carnitine: an old friend comes out from the shadow

Necroptosis is characterized by the excessive accumulation of the products of oxidative stress, such as lipid hydroperoxides [218], end products of glycation [219], and increased activity of bioenergetic pathways, including glutaminolysis [220, 221]

doi: 10.1016/j.ijdevneu.2015.04.003

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Moreover, FXR has been shown to modulate lipid metabolism by influencing the expression of genes involved in triglyceride and cholesterol metabolism

The majority of acylcarnitine is excreted in the urine, allowing for the excretion of abnormal metabolites
