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Although small statistical power of the current study the significant difference between patients with depression and the control group for thePro197LeuGSH-Pxpolymorphism indicates that the distribution of these alleles may have a contribution in the physiopathogenesis of depression

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Current therapies mainly focus on disease modification by immunosuppression, while no treatment specifically focuses on controlling cell death injury

Laboratory investigations reveal that 5-amino-1MQ suppresses lipogenesis in adipocytes with an EC of 30 M, mechanistically achieved through restoration of cellular NAD+/SAM ratios that favor lipolysis over lipid storage

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