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Goldberg 44 Philip Goldberg 44, November 24, 2000, in Salem, Oregon

Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver

Based on the in-depth understanding of glutamine metabolic pathways, the development of molecular drugs that specifically target glutaminase or transporters offers innovative strategies to combat tumor growth and curb tumor progression