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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Arias-Barrau E, Dirusso CC, Black PN

Vitiligo treatments Macules caused by vitiligo are often difficult to treat

doi:10.1002/9780470973639

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Furthermore, it is able to genotype at viral loads of 500 IU/mL and below depending on the genotype 39

Reportedly, PTEN loss in melanoma is a frequent event, occurring in about 30% of primary tumors, with an even higher frequency in melanoma cell lines ( The TP53 gene is considered the guardian of the genome due to its pleiotropic function in protecting cells from genotoxic damages, acting as tumor suppressor and transcriptional activator/repressor of several downstream genes controlling cell-cycle progression, DNA repair, and also triggering apoptosis ( TP53 mutations have been reported in about 15% of TCGA cases, they are mostly ultraviolet (UV) radiation-induced, and lead to tumor initiation and progression