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98 In addition, Muc2 gene mutation in mice can induce endoplasmic reticulum stress in intestinal epithelial cells, and the misfolding of intrinsic proteins in the intestinal epithelium triggers the inflammatory response of intestinal epithelial cells, thereby destroying the structure and function of the intestinal barrier in mice and promoting the progression of UC by affecting the intestinal microbiota

All animals in Groups 14 were evaluated for clinical observations, body weights, and clinical pathology (hematology, coagulation, and serum chemistry), gross necropsy observations and major organ weights

At both sites, IGF-1 and IGFBP-3 correlated positively with total energy and fat

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