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EBNA-1 exhibits molecular mimicry with self-antigens [212, 222,223,224,225,226], generating IgG against these self-proteins, and/or a specific cellular response

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In symptomatic SOD1 G93A mice, because no decrease in Gpx4 mRNA level was observed, the deficiency of Gpx4 likely occurred at the post-transcriptional level

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Regular lab tracking and clinician oversight help keep dosing in a safe, appropriate range

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