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Multiple studies (in vitro and in vivo) demonstrate the association between IGF-1 deficit and deregulated lipid metabolism, cardiovascular disease, diabetes, and an altered metabolic profile of diabetic patients

In this review, we highlight the fact that the classical senolytic approach based on drug repurposing display limited efficacy and probably reached its limits in term of clinical development

PMID 302667

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Someone has addressed obvious triggers, improved air quality, changed their diet, and started rebuilding energy, but they still feel irritated airways, thick mucus, or a persistent sense of pulmonary stress

For the vascular side, GHK-Cu promotes angiogenesis through VEGF and bFGF expression, improves blood vessel integrity, and supports microcirculation