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Readers interested in how the same molecule is being examined from the appetite side can compare this analysis with the companion discussion of cagrilintides role in appetite regulation, which focuses on the central satiety arm rather than the gastrointestinal one

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Among the major drugs that are in development, we observe some already in Phase III: inhibitors of the -site amyloid precursor protein cleaving enzyme (BACE) (CNP520, LY3314814, and verubecestat) and antibodies against the A peptide (aducanumab, solanezumab, crenezumab, gantenerumab, and BAN2401) [22, 27]

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The relative expression levels of each gene were quantitated using the 2 CT method and normalized to the amount of endogenous glyceraldehyde-3-phosphate dehydrogenase (GAPDH)