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EHA Abstract 2021

In that respect, the mathematical model suggests that this robustness may be inherently encoded in the negative feedback as the neural outputs were largely insensitive to a wide range of changes in the system's parameters (Appendix Fig S2)

Columbia, NEC) in response to TMV and TNV infection suggest that, in addition to SA, GSH may also contribute to the elevated virus resistance of NEC (Kirly et al., 2024)

Knockout of prolyl hydroxylase domain-containing protein 2 (PHD2) stabilized HIF-1 protein and activated HIF-1 signaling, which transcriptionally upregulated glutaminase 1 ( GLS1 ) expression leading to a decrease in ROS production and increases in cellular GSH levels, GSH/GSSG, and cell survival in murine periosteal progenitor cells, suggesting that HIF-1 signaling promotes glutaminolysis to provide glutamate for GSH synthesis (96)

Viscosity regulation Ambroxol stimulates serous secretion and increases airway surface liquid depth, in addition to thinning of the thick mucus and sputum