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Notably, these pathways may converge on shared targets, such as BDNF expression, highlighting potential overlaps and synergistic effects between these nutrients

GSH depletion was negatively correlated to motor function performance

Clinical trials are needed to assess the safety and efficacy of these approaches in humans and to determine their potential to halt or reverse the DKD progression

Glutatyon (Setria) 500 mgVitamin B2 (Riboflavin 5'-Fosfat) 10 mgVitamin B6 (Piridoksal 5'-Fosfat) 10 mgPirolokinolin Kinon (PQQ) 5 mgSelenyum 40 mcg , Molibden 35 mcg

Notably, the SVM provided the overall best performance for our dataset because it is a machine learning approach for binary classification and can handle the smaller datasets well ( Supplementary Table 1 )