enzyme glutathione peroxidase 1 peroxidase-1 and neuromodulation: Novel potentials of an old Team:UNSW Australia/Model/Glutathione System

The online consultation is straightforward and completely confidential youll answer questions about your periods, medical history, and current symptoms

CYP1A1 metabolism of estrogen, polyaromatic hydrocarbons, and more CYP1A2 metabolism of caffeine, duloxetine, bupropion, aflatoxin B, and more CYP2A6 metabolism of nicotine, coumarin, and more CYP2B6 metabolism of ketamine, methadone, sertraline, and more CYP2C9 metabolism of warfarin, rosuvastatin, celecoxib, and more CYP2C19 metabolism of clopidogrel, some proton pump inhibitors, more CYP2D6 metabolism of some antidepressants, antipsychotics, more CYP3A4 metabolism of half of all prescription drugs CYP2E1 metabolism of fatty acids, alcohol, and some anesthetics Phase II detoxification genes: UGT, GST, Nrf2 Phase II detoxification involves taking the metabolites of phase I and modifying them to be easily excreted through conjugation with sulfur, glutathione, glucuronic acid, amino acids, or methyl groups

PMID: 34268329

doi: 10.3389/fgene.2016.00136 56 DenkertCBudcziesJKindTWeichertWTablackPSehouliJet al

Ongoing studies provide remarkable evidence that oxidative stress is involved in reproductive toxicity induced by various stimuli, such as environmental toxicants and food toxicity

For instance, in ovarian cancer, a study demonstrated that curcumin induced autophagy via the inhibition of the AKT/mTOR/p70S6K signaling pathway, enhanced light chain (LC)3B-I/II expression and increased autophagy related 3 and Beclin1 expression in a concentration-dependent manner (49)