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[DOI] [PubMed] [Google Scholar] Asara J
Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells
Hydrolysis and transfer reactions catalyzed by -glutamyl transpeptidase
The mutation of m6A consensus sequences were generated by substituting adenine for thymine
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Such findings underscore the significance of microbial metabolites as potent bioactive molecules that can be harnessed to boost immunotherapeutic strategies and support tissue regeneration in chronic diseases
In line with this, CLL lymphocytes also have overexpressed glutamine dehydrogenase, which plays a role in glutathione synthesis, and abolishing the glutathione-mediated protection mechanism leads to apoptosis of CLL cells (81, 82)
