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Vitamin B12 plays a crucial role in: Red blood cell production Brain and nerve function DNA synthesis Energy metabolism A deficiency can lead to symptoms like: Fatigue and weakness Poor concentration or memory Pins and needles Pale skin Low mood or irritability If left untreated, long-term deficiency can cause nerve damage and other health issues

Active site loop composition impacts L1 GUS inhibition By comparing the IC 50 values determined in this study, we found that the L1 Cluster GUS enzymes were not inhibited, or poorly inhibited, by the bacterial GUS inhibitors (Table 2)

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Luteococcus peritonei, Planococcus chinesis, Pseudarthrobacter polychromogenes, and Streptococcus spp

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