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Zinc could be involved in the atherogenic process through interaction with atherogenic cells, such as endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and immune cells

Additionally, in oxidative stress cells, Tripartite Motif Containing 22 (TRIM22) has been found to interact with Keap1 and accelerate the ubiquitination and degradation of NRF2, thereby inhibiting oxidative stress progression and activating ROS/AMPK/mTOR/autophagy signaling pathways

[DOI] [PubMed] [Google Scholar] 200.Ali Y, Monini C, Russeil E, Ltang JM, Testa E, Maigne L, Beuve M

Drug-nutrient interactions may further intensify these effects

[DOI] [PubMed] [Google Scholar] Djurii A

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