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1st reaction: conversion of glucose to glucose-6 phosphate

Most process development analytics only measure extracellular variables, ignoring the intracellular environment (10)

The samples were thawed and homogenized in 1:9 w/v ice-cold normal saline

PO phenytoin has ~90% bioavailability, so a 1:1 conversion is often used to convert between PO and IV administration

5.2 Birth Defects Valproate can cause fetal harm when administered to a pregnant woman

Randall et al
