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Even low Cd concentrations can negatively affect numerous metabolic processes by replacing essential metal ions in both humans and plants that, in turn, disturbs the activities of essential enzymes (Farooq et al., The mobility of cadmium in soil and water is very high, which makes it possible for the metal to be easily translocated and accumulated by plants

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From a market perspective, the demand for antifungal drugs continues to rise: The market is expected to expand at a compound annual growth rate (CAGR) of 2.81% from 2020 to 2033, with a size of 14.09 billion US dollars in 2024, expected to rise to 14.48 billion US dollars in 2025, and reach 18.08 billion US dollars by 2033 ( Figure 1 ) (Insights, 2025).However, the development and application of antifungal drugs face numerous challenges (Fisher et al., 2018

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[DOI] [PubMed] [Google Scholar] 373.Shenouda, S
