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After 28 days, the cumulative risk of contamination from repeated entries and the potential for gradual degradation of the benzyl alcohol become too significant to ignore

on the grounds that it could create serious damage to other cell populations by inducing massive free radical production instead [39]

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and the potential to induce a host immune response against the tumor cells (Eder et al., 2009)

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Daily (or multiple daily) injections are required