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Cystatin, a protein inhibitor of cysteine proteases alters viral protein cleavages in infected human cells

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Termination of GPCR signaling Termination of signaling requires turning off activated receptors, turning off activated G-proteins, and return of second messenger levels, protein phosphorylation levels, and other changed metabolites to their original values

GnRH agonists create a hypoestrogenic, hypogonadal environment and subsequent down-regulation of gonadotropin secretion resulting in decreased estrogen production

To mitigate the effect of off-target gene silencing, sgRNAs with a 12 bp seed region matching any other site in the genome (adjacent to a PAM site) were removed

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