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The research identifies a dysfunctional EIF3H/YAP proteolytic axis as a key mediator between cancer-associated adipocytes and drug response

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doi: 10.1038/nri2190 17 BeckmannY.UzunkprC.SubaoluA

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The trials used doses ranging from 0.25 mg to 54 mg daily (well above typical protocols) for durations up to 24 weeks

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