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Calagualine inhibits nuclear transcription factors-B activated by various inflammatory and tumor promoting agents
It is not a drug, cosmetic, food, or supplement, and it is not intended for human consumption, therapeutic application, diagnostic use, or veterinary use
Virulent factor ESAT-6 drives macrophage differentiation toward the pro-inflammatory M1 phenotype and subsequently switches it to the anti-inflammatory M2 phenotype
Therefore, we used the higher dose in subsequent experiments
