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doi: 10.3390/antiox6010020

Small molecule inhibitors as tools to scan for active pathways do not conclusively rule out the participation of a signaling mediator if a negative result is obtained (i.e., no inhibition/augmentation of a toxic endpoint)

The KD was also shown to increase anti-inflammatory responses in glaucomatous mice, evidenced by increased expression of Arginase 1, a marker of neuroprotective anti-inflammatory microglia, as well as increased expression of the anti-inflammatory cytokine IL-4 in retinas and optic nerves (40)

Side effects are rare but may include mild swelling at the injection site

Without FDA approval, these products are made by compounding pharmacies that are not required to track, evaluate, or report side effects and adverse events

Supplementary Data 5 (download XLSX Statistical supporting data for Supplementary Fig