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However, current treatments are not effective in preventing the occurrence of end-stage renal disease, blindness, disability, and other adverse outcomes, therefore, discovering new therapeutic targets is of utmost importance

Results In untreated rats, a large defect appeared between the cut ends of the Achilles tendon

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Some participants achieved weight loss of approximately 24% of body weight at 48 weeks approaching levels reported with some bariatric surgical procedures, though no direct head-to-head comparisons have been conducted and long-term durability beyond the trial period remains unknown

The systemic effects of AKI that may contribute to mortality have been extensively investigated in preclinical models

30 LiuJ.QiaoB.DengN.WuY.LiD