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HCT-116 CRC cells were seeded in 6-well plates at 15 10 4 cells per well

Higashio K, Shima N, Goto M, Itagaki Y, Nagao M, Yasuda H, et al

Kantono K, Hamid N, Chadha D, Ma Q, Oey I, Farouk MM

Follow up as scheduled to assess response and adjust the protocol if needed

All the generated 3D all-atom models were optimized by using the FOLDX repair tool 103 and then energetically minimized using the Yasara Minimization server 104 or the Rosetta relax application within the Rosetta scoring and prep tools 105,106 , independently

Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors
