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FDA lacks important information regarding any safety issues raised by KPV, including whether it would cause harm if administered to humans.18 In other words, there have been no dedicated safety studies on KPV, so its status as a safe or unsafe therapy is up in the air

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Therefore, sensitization of the A- and C-fibers was apparent one day after incision

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While KPV has shown promise in preliminary studies, the FDA requires more comprehensive data before allowing its widespread use in compounded medications