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81 In an abstract of the 2022 Society of Gynecologic Oncology (SGO) Annual Meeting, Borden and colleagues described a retrospective study of 18 recurrent EC treated with single-agent pembrolizumab, and found that that recurrence-free survival and OS was significantly decreased in patients with epigenetic MMR-D (n=12)

Chen H, Zhang B, Yao Y, Chen N, Chen X, Tian H et al (2012) NADPH oxidase-derived reactive oxygen species are involved in the HL-60 cell monocytic differentiation induced by isoliquiritigenin

doi: 10.3109/10715762.2015.1089988 42 NagyPAshbyMT

Research suggests that genetics and environmental factors might be the main cause

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