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Description
In the pivotal 2018 animal study by Neelakantan et al., systemic treat Mechanism of Action 5-Amino-1MQ inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that catalyzes the N-methylation of nicotinamide using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH) as products

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AOD-9604 does not bind the growth hormone receptor (GHR), the activation step that triggers IGF-1 release
However, noticeable effects take longer to manifest

PMID:39161060 Liu M, et al
Rarely, individuals may experience more severe reactions, such as anaphylaxis, which requires immediate medical attention
