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doi: 10.1016/S0261-5614(98)80304-X

Cell Factories 21:29

If you experience any of the following side effects after taking folic acid or a supplement like ferrous ascorbate and folic acid tablets, be sure to contact your doctor right away: Fever Feeling generally weak or uncomfortable Shortness of breath Feeling itchy, or experiencing a skin rash or reddened skin Difficulty breathing Wheezing A tight feeling in your chest Harvard Health: "Iron and Your Health" Johns Hopkins Medicine: "Folate-Deficiency Anemia" National Institutes of Health: Office of Dietary Supplements: "Iron" Mayo Clinic: "Folate (Folic Acid)" University of Rochester Medical Center: "What Are Red Blood Cells?" Amway: "Nutrilite Iron Folic" Vitamin Shoppe: "MegaFood: Blood Builder With Whole Food Iron & Organic Beet Root: Supplement Facts" University of Michigan: Rogel Cancer Center: "Why Is Iron Important in My Diet?" Mayo Clinic: "Folic Acid (Oral Route, Injection Route)"

The reclassification to Category 2 may serve as a catalyst for pharmaceutical companies and research institutions to invest in the rigorous clinical trials required for formal FDA approval