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[PUBMED Abstract] Bader P, Rossig C, Hutter M, et al.: CD19 CAR T cells are an effective therapy for posttransplant relapse in patients with B-lineage ALL: real-world data from Germany

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(ii) ROS generation is coupled to energy production and cellular activity 40
Development was discontinued after the compound repeatedly failed to convert its consistent GH/IGF-1 effect into approved clinical benefit most visibly a completely negative 563-patient Alzheimers trial and after a hip-fracture Phase IIb study was terminated early for a congestive-heart-failure safety signal

Aging increases the risk of HCC by promoting cellular senescence, chronic inflammation, and metabolic dysregulation (Wong et al., 2021

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