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Although the beneficial roles of astrocytes in the maintenance of neuronal function have long been recognized, recent advancements in research have begun to alter the perspective regarding their function and role in the brain, suggesting that their contributions should be examined at the cellular level 11

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Autonomic dysfunction Autonomic dysfunction in ME/CFS manifests through diverse symptoms, primarily encompassing neurocardiovascular issues like orthostatic intolerance and postural orthostatic tachycardia syndrome (POTS), as well as neurogastrointestinal disturbances [199]

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