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We also tested the thermal stability of the studied compounds

Metabolic monitoring We track insulin resistance markers, lipid panels, and liver enzymes not just weight because meaningful metabolic improvement is the goal, not just a lower number on the scale

Further studies should include testing the efficacy of different molecules (cyano-, hydroxo-, methyl-cobalamin) and dosages
One practical consideration: higher-concentration solutions (2000mcg/mL or above) increase the risk of peptide aggregation during long-term storage, so unless your protocol specifically requires minimal injection volumes, a 1000mcg/mL concentration is the safer choice for multi-week studies
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ITR and DSI are correlated