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Although these findings have generated considerable interest, most of the available evidence comes from laboratory and animal studies rather than large human clinical trials

Digestive comfort

This mechanism is considered a physiological basis of the behavioral sickness response that humans and animals display during infections (Poon et al., 2015)

Insufficient SAM allows histamine to accumulatecontributing to headaches, restlessness, poor sleep. Neurotransmitter metabolism : SAM supports the conversion and breakdown of dopamine, norepinephrine, and epinephrine via COMT and PNMT

Cumulative gamma power during AW was also unaffected during SD (n.s., data not shown)

If you are pregnant or nursing , consult your healthcare professional before use