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Many synthetic, medicinally active substances, including non-steroidal anti-inflammatory medicines (NSAIDS), aminoglycosides, antibiotics, and chemotherapeutic drugs, can impact the urinary system and cause acute renal failure, nephritis, and other kidney-related conditions

Villani RG, Gannon J, et al

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When risk factors are identified based on history, selective screening for heavy metal toxicity is warranted

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