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Imai H, Hirao F, Sakamoto T, Sekine K, Mizukura Y, Saito M, et al

The role of protease-antiprotease imbalance in emphysema

doi: 10.1158/1940-6207.capr-08-0178

This mitochondrial failure results in the immune senescence of those same T cells and a systemic accelerated aging phenotype, marked by motor deficits, cardiovascular dysfunction, and cognitive decline (Desdn-Mic et al., 2020)

Frazie MD, Kim MJ, Ku KM

In the event that a patient appears to have suboptimal levels or deficiency, treatment with B 12 would not be costly, is unlikely to adversely affect the patient, and may optimize surgical outcome
