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GI problems, such as constipation and diarrhea, are also common and exacerbated by limited dietary variety and fiber intake

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(37) reported that the mRNA expression of IL-1 in cultured bovine alveolar macrophages reached its maximum at 1 to 2 h following incubation with LPS from Pasteurella haemolytica and was not detectable 24 h after stimulation, indicating a downregulation of this cytokine

Compendium on Continuing Education for the Practicing Veterinarian 1999;21:235-237