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The theory is that saturating hepatic methionine stores accelerates the initial metabolic shift

102,201 A recent study conducted in the Japanese revealed that even among healthy, lean, normotensive individuals, the presence of hyperuricemia is associated with an elevated risk of cardiometabolic disease

Circulation 146 , e18e43 (2022)

J Am Coll Cardiol 49: 22312237, 2007
Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity

doi:10.3389/fncel.2019.00353
