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More serious concerns include infection, allergic reactions, or nutrient overdoses, especially if oversight is lacking.

Special care must be taken when diazepam is used during labor and delivery, as high single doses may produce irregularities in the fetal heart rate and hypotonia, poor sucking, hypothermia, and moderate respiratory depression in the neonates

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That women commonly develop hypercalciuria in pregnancy is an indication that they normally absorb more calcium than needed by the fetus, provided that their calcium intake is not low, or that the gastrointestinal absorption of calcium is not impaired by high phytate consumption or malabsorptive disorders

In addition, ALDH *2/*2 was present only in patients, and the GSTT1 null genotype was associated with AUD [11]

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