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Young children and infants are particularly susceptible to even low amounts of lead, and there is a significant reduction of cognitive function that has been reported by Rubin and Strayer (2008)

COVID-19, aging, and neurodegenerative disorders share five events that end up in ferroptosis, which are neuroinflammation, iron dysregulation, anti-oxidant defense repression, ACE2/Ag II disruption, and clock gene alterations

J Transl Med 10 , 224 (2012)

Its effects on BDNF-related pathways and synaptic plasticity make it theoretically relevant to depression, though direct antidepressant research is limited