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1 Introduction Community-acquired pneumonia (CAP) refers to the infectious inflammation of the lung parenchyma (including the alveolar wall, i.e., pulmonary interstitium in general) acquired outside of hospitals, including pneumonia caused by pathogens with proven latency ( coronavirus disease 2019 (COVID-19) has put unprecedented pressure on healthcare worldwide and incurred non-negligible medical costs ( 2 Occurrence of CAP and activation of the immune response The lung is a complex microbial ecosystem

Patnaik R, Varghese R, Al Kabani A, Jannati S, Banerjee Y

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Oxidative stress and mitochondrial dysfunction are considered central features of neurodegenerative diseases [26], and the long-term use of KD may positively affect mitochondrial function through several mechanisms

Allelic variants of CYP3A4 have also been reported but their contribution to its well-known interindividual variability in drug metabolism apparently is limited

Zamberletti E, Beggiato S, Steardo L Jr, Prini P, Antonelli T, Ferraro L, et al