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and the stem cell markers OCT4 (Forward: 5-GAGCCCTGCACCGTCACC-3 and Reverse: 5-TTGATGTCCTGGGACTCCTCC-3), SOX2 (Forward: 5-TACAGCATGTCCTACTCGCAGC-3 and Reverse: 5-GAGGAAGAGGTAACCACAGGGG-3), CXCR4 (Forward: 5-ACTACACCGAGGAAATGGGCT-3 and Reverse: 5-CCCACAATGCCAGTTAAGAAGA-3), and cMET (Forward: 5-AGCGTCAACAGAGGGACCT-3 and Reverse: 5-GCAGTGAACCTCCGACTGTATG-3) for 30 cycles using GoTaq qPCR Master Mix (Promega, Madison, WI, USA)

WT- and T315I-Bcr-Abl-32D cells show differential vulnerability to JMF4073 treatment

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CONCLUDING REMARKS AND FUTURE PERSPECTIVES Overall, the role of Nrf2 activation in cancer is paradoxical and requires further exploration

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