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The resulting free fatty acids exit the fat cell through fatty acid transport proteins and enter the bloodstream

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In the fourth and last stage of B12 deficiency, clinical manifestations are experienced by the individual including macrocytic anemia (a form of anemia in which red blood cells are larger than usual, hence the term macro) and, if left untreated, irreversible neurological damage

AbbVie continues to explore new treatment pathways to address the diseases progression

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doi: 10.1371/journal.pone.0062934